Ebastine is a second-generation antihistamine, available in brand names Kestine, Ebaget, Atmos has been demonstrated to be helpful in the treatment of allergic rhinitis, both seasonal and perennial. Ebastine is an H1 antihistamine with a modest drowsiness risk. It does not permeate the blood–brain barrier very well, combining an effective inhibition of the H1 receptor in peripheral tissue with a low prevalence of central side effects, such as sedation and tiredness.