Levosulpiride | A Prokinetic Agent

Introduction Levosulpiride avaiable under the brand of Levopraid, is an atypical antipsychotic medication. It is used to treat psychiatric disorders such as depression, schizophrenia, vertigo, and hallucinations. However, it can also be used to treat digestive issues such as GERD, IBS, indigestion, and chronic heartburn. It is also prescribed by doctors to prevent premature ejaculation.
Class of Medicine Levosulpride | A Prokinetic Agent,  belongs to the antipsychotic medication class (also known as neuroleptics or tranquillizers). It is mostly used to treat hallucinations, schizophrenia, bipolar disorder, anxiety, and vertigo, among other mental illnesses.
Mode of Action The main mechanism of action of levosulpiride is to block the D2 dopaminergic receptors, which are preferentially located on the presynaptic membranes in the brain’s dopaminergic pathways; this means that sulpiride is a selective autoreceptor blocker.
Medical Uses Levosulpiride is used to treat the following conditions:

Psychosis
Schizophrenia’s negative symptoms
Anxiety problems
Dysthymia
Vertigo
Dyspepsia
Irritable bowel syndrome (IBS)
Ejaculation occurs too soon.
In the United Kingdom and other European countries, levosulpiride is not currently approved for the treatment of premature ejaculation.

Avaiability & Usage Levosulpride is available in tablet form. Should be taken only on your doctor’s prescription. Take LEVOSULPIRIDE with or without food. The tablet form of LEVOSULPIRIDE should be swallowed as a whole, do not crush, or break the tablet.
Side Effects Patients taking levosulpiride frequently experience the following side effects:

Amenorrhea is the absence of menstrual periods.
Gynecomastia is a condition in which men’s breasts become enlarged.
Changes in sex motivation
Galactorrhea is the discharge of milk from the nipples when a woman is not breastfeeding.
If levosulpiride is not taken as directed, it can cause serious health problems.

The following are rare but serious side effects:

A potentially fatal condition characterised by a high fever
Breathing and heart rate are both fast.
Pulse irregularity
Confusion
Sweating
Neuroleptic malignant syndrome is characterised by a significantly altered mental state.

Important Warning Patients with a history of neuroendocrine tumours, epilepsy, manic states, abnormally high levels of prolactin in the blood, painful, lumpy breasts, heart disease, any allergy, and during pregnancy and breastfeeding should exercise caution.
Available Brands Levopraid